BioNMR in drug research


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The book is not only of interest to specialists in pharmaceutical research and development, but will certainly also be a valuable resource for everyone concerned with the latest methods of NMR spectroscopy and their application to biomolecules" Angewandte Chemie Int.


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The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt Wuthrich. Editied by a former coworker of Wuthrich, this book presents the theoretical background on NMR of biomolecules, plus the use of NMR techniques in determining the structures of proteins and nucleic acids. BioNMR spectroscopy offers a universal tool for examining the binding of an active substance to its target protein.

Structure and Dynamics of Nucleic Acids and Interacting Proteins by NMR Spectroscopy

Its use thereby benefits the rational development of drugs. This interaction can now be investigated in a hitherto unparalleled precision and displayed in 3D-an important prerequisite for the targeted development of new active substances, The latest methods for characterizing substance-receptor complexes are demonstrated backed by many case studies from pharmaceutical reseach. Thus it comes as no surprise that a large number of the authors are working for leading pharmaceutical companies.

With its successful mixture of basic information and application strategies, coupled with many real-life examples, this is an invaluable guide for both NMR spectroscopists and pharmaceutical researchers. Edited by a former coworker of Wuthrich, this book presents the theoretical background on NMR of biomolecules, plus the use of NMR techniques in determining the structures of proteins and nucleic acids.

BioNMR in Drug Research (Methods and Principles in Medicinal Chemistry, V. 16)

Blommers, et al. Pellecchia, et al. Subject Index. Du kanske gillar.

BioNMR in Drug Research (Methods and Principles in Medicinal Chemistry, V. 16) - PDF Free Download

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  4. Skickas inom vardagar. The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt Wuthrich.

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    Edited by a former coworker of Wuthrich, this book presents the theoretical background on NMR of biomolecules, plus the use of NMR techniques in determining the structures of proteins and nucleic acids. Australian National University Library. Open to the public. Deakin University Library.

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    Open to the public ; Barr Smith Library. University of Western Australia Library. Campbelltown Campus Library.


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    Open to the public ; Online : Licence restrictions may apply Book; Illustrated English Show 0 more libraries None of your libraries hold this item. Found at these bookshops Searching - please wait We were unable to find this edition in any bookshop we are able to search. These online bookshops told us they have this item:.

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    CHAPTER 2: DRUG DISCOVERY AND DEVELOPMENT

    Australian National University. Deakin University. Queensland University of Technology.

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